Perinatal Hepatitis B Prevention Program


The Perinatal Hepatitis B Prevention Program (PHBPP) aims to prevent hepatitis B transmission from pregnant women to their infants as well as their household and sexual contacts. Prevention of perinatal hepatitis B transmission requires the coordinated efforts of primary care providers, hospitals, laboratories, and the state and local health departments.

Detailed information for preventing perinatal hepatitis B infections can be found in the PHBPP Manual.

KEY COMPONENTS TO PREVENTING PERINATAL HEPATITIS B INFECTIONS

PHBPP Ket Components

For additional information, please call the PHBPP Coordinator, Elizabeth Lawlor, at 785-368-8208 or the Kansas Epidemiology Hotline at 877-427-7317.

YOUR ROLE IN PREVENTING PERINATAL HEPATITIS B

IF YOU ARE A PRENATAL CARE PROVIDER

(PHBPP Manual - Chapter 7)

  • Test every pregnant woman during each pregnancy for HBsAg even if they have been previously vaccinated or tested
  • Inform pregnant women of their HBsAg status
  • Send a copy of the HBsAg test result for current pregnancy with prenatal records to the delivery hospital
  • Report all HBsAg-positive pregnant women to KDHE within 7 days (even if they were previously reported) using the Prenatal Care Provider Report Form
  • Counsel HBsAg-positive pregnant women about their status and refer for appropriate care
  • Assess HBsAg-negative pregnant woman's risk for hepatitis B virus (HBV) infection
  • Counsel HBsAg-negative pregnant woman on methods to prevent HBV transmission
  • Retest high risk pregnant HBsAg-negative women in their last trimester

IF YOU WORK IN THE HOSPITAL LABOR AND DELIVERY UNIT OR IN THE NURSERY UNIT

(PHBPP Manual - Chapter 8)

  • Review and record the maternal HBsAg test result for the current pregnancy on both labor and delivery record and on infant’s delivery summary sheet
    • If a woman presents with an unknown HBsAg status or with risk factors, test STAT
    • If STAT test is HBsAg-positive, report to KDHE within 24 hours (even if they were previously reported)
  • Give all infants single-antigen hepB vaccine at birth
  • Give all infants born to HBsAg-positive women single-antigen hepB vaccine and HBIG within 12 hours of birth
  • Report all HBsAg-positive women and the HBIG and hepB administration to the PHBPP (if you were not contacted prior to delivery, the PHBPP may not be aware of mom’s HBsAg status), using the Hospital Report Form

IF YOU PROVIDE PEDIATRIC CARE

(PHBPP Manual - Chapter 9)

  • Know the maternal HBsAg status for all infants to whom you provide care (if mom is HBsAg-positive and you were not contacted, the PHBPP may not be aware of her status and will need to be notified)
  • Complete the recommended hepB vaccine series and post-vaccination serology for all infants born to HBsAg-positive women
    • If the infant is HBsAg negative and anti-HBs positive, then infant is protected
    • If infant is HBsAg and anti-HBs negative, repeat three doses of hepB vaccine and retest one month later
    • If the infant is HBsAg-positive, counsel the family and refer the infant for appropriate care
  • Report hepB administration and post-vaccination serology results to the PHBPP using the Pediatric Care Provider Form

IF YOU ARE A LOCAL HEALTH DEPARTMENT

(PHBPP Manual - Chapter 6)

  • Educate clients on the risks and prevention of disease transmission
  • Notify the hospital of the mother’s hepatitis B status
  • Ensure infants born to hepatitis B positive mothers receive appropriate prophylaxis at birth;
  • Notify the pediatric care provider of the mother’s hepatitis B status and ensure infants complete the vaccination series and post-vaccination serology (PVS) testing on time
  • Ensure household and sexual contacts are serologically tested and vaccinated, when necessary
  • Update the disease surveillance system, EpiTrax, for hepatitis B positive mothers, their infant(s), household and sexual contacts within 15 days of most updated case management activity

REPORTING FORMS

REPORTS

ADDITIONAL INFORMATION

Kansas Department of Health and Environment
Home page: www.kdheks.gov
Infectious Disease Epidemiology and Response: http://www.kdheks.gov/epi/index.html
Viral Hepatitis Prevention: http://www.kdheks.gov/hiv/hepatitis.htm
Immunization Program: http://www.kdheks.gov/immunize/index.html

Centers for Disease Control and Prevention
Home page: www.cdc.gov
National Immunization Program: www.cdc.gov/vaccines
Division of Viral Hepatitis: www.cdc.gov/hepatitis
Pink Book-Epidemiology and Prevention of Vaccine Preventable Diseases: www.cdc.gov/vaccines/pubs/pinkbook/default.htm
Vaccine Information Statement (VIS): www.cdc.gov/vaccines/pubs/vis/default.htm

General Resources
Advisory Committee on Immunization Practices (ACIP): www.cdc.gov/vaccines/recs/acip/default.htm
American Academy of Pediatrics (AAP): www.aap.org
American College of Obstetrician and Gynecologist (ACOG): www.acog.org
American Liver Foundation: www.liverfoundation.org
Asian Liver Center at Stanford University: http://liver.stanford.edu
Hepatitis B Foundation: www.hepb.org
Hepatitis B Moms: www.hepbmoms.org
Hepatitis Foundation International: www.hepfi.org
Immunization Action Coalition: www.immunize.org
Pink Book-Epidemiology and Prevention of Vaccine Preventable Diseases: www.cdc.gov/vaccines/pubs/pinkbook/default.htm
Red Book - Report of the Committee on Infectious Diseases: www.aap.org/bookstorepubs.html